Two Assistant Professor of Cancer Biology at Biotech Research
Faculty of Health and Medical Sciences
University of Copenhagen
We are seeking two Assistant Professors for 2-year positions starting 1 September 2023 to explore experimental approaches to discover new ways to target the mechanisms of development of chemoresistance in ovarian cancer in the Wennerberg group at BRIC, Faculty of Health and Medical Sciences, University of Copenhagen
Information on BRIC and the Wennerberg group can be found at: www.bric.ku.dk
The Wennerberg group at BRIC focuses on identifying new effective precision cancer therapies. This is done with a systems-driven approach where we combine chemical biology, phenotypic profiling, molecular profiling, and informatics to gain an understanding of individual cancers, their drug resistance mechanisms, and how they may be targeted. Our ultimate goal is to build the foundation for new types of stratified and individualized cures for cancer patients.
The assistant professors’ responsibilities will primarily consist of research, including publication/academic dissemination duties.
The first Assistant Professor will take the lead on a project focused on identifying novel targetable mechanisms of phenotypic plasticity underlying ovarian cancer chemoresistance. The project integrates high-throughput lineage phenotyping and drug response analyses in ovarian cancer organoids with functional genomics and molecular profiling. The project involves several collaborating parties in Europe, and the role involves coordinating the experimental planning and smooth data flow between the collaborators.
The second Assistant Professor will lead efforts in exploring new therapeutic targets in ovarian cancer that could overcome chemoresistance to conventional chemotherapy. This will involve handling and working with primary cell culture models of ovarian cancer, high throughput screening, high content imaging, molecular profiling. In addition, you will be leading our work on developing new organoid models and biobanking. The organoid development includes several national and international collaborators and you will be responsible for coordinating collaborative efforts.
Both of you will be encouraged to further design and implement innovative methodologies to address the clinically relevant questions in the ovarian cancer therapy resistance field, depending on her/his expertise and interests.
Teaching at Master’s, PhD, and medical student courses organized at BRIC will also be part of your tasks.
Six overall criteria apply for assistant professor appointments at the University of Copenhagen. The six criteria (research, teaching, societal impact, organisational contribution, external funding, and leadership) are considered a framework for the overall assessment of candidates. Find information about each criterion here: https://employment.ku.dk/faculty/criteria-for-recognising-merit.
Furthermore, we are looking for highly motivated and enthusiastic scientist with the following skills and experience:
Essential experience and skills:
- You have a PhD in life sciences
- Postdoctoral research experience
- Extensive experience in in vitro models of solid tumours and organoid technology.
- Extensive experience with high-throughput screening and high-content imaging assay design.
- Excellent writing skills and experience in writing research articles, grant applications, and reports to funding bodies.
- Experience in training and supervising students and junior researchers.
- Experience in leading research projects and managing collaborations between multiple research sites.
- Efficient communication skills and ability to work in a team.
- Ability to multitask and manage competing priorities.
- Proactive problem-solving attitude.
- Excellent written and spoken English.
Specifically for the first position, the following experience and skills are required:
- Extensive experience in CRISPR gene editing and functional genomics. Multi-omics research experience is an asset.
- Solid expertise in molecular biology and next-generation sequencing (NGS).
- Documented experience in DNA barcoding technology.
- Animal experimentation experience and FELASA certification.
Specifically for the second position, the following experience and skills are required:
- Documented experience in developing new organoid models, including developing new methods for organoid culture.
- Molecular profiling of in vitro models of solid tumours.
Desirable experience and skills:
- Experience with ovarian cancer research.
Place of employment
The place of employment is at BRIC, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 24 research groups at BRIC and the neighbouring Finsen Laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers association, ASAP, our own PhD programme, MoMeD and our own Postdoc Career Programme. BRIC actively participates in the European alliance, EU-life consisting of 13 excellent life science research institutions http://eu-life.eu/
Terms of employment
The employment as assistant professor is a full time and fixed-term position for 2 years. Starting date is 1 September 2023.
Salary, pension and other conditions of employment are set in accordance with the agreement between the ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 38,000 DKK/approx 5,100 EUR (April 2023 level). Depending on qualifcations, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.
Foreign and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
For further information please contact Krister Wennerberg; firstname.lastname@example.org.
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Your application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (Max. one page)
- CV incl. education, work/research experience, language skills and other skills relevant for the position
- A certified/signed copy of a) PhD certificate and b) Master of Science certificate.
- List of publications
Deadline for application: 7 June 2023 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
Interviews are expected to be held in week 26-27.
The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.
Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.