Postdoc position at NNF Center for Protein Research

A highly attractive postdoctoral position is available in the Choudhary group at the Novo Nordisk Foundation Center for Protein Research (CPR – www.cpr.ku.dk), University of Copenhagen. Commencing on 15 April 2023 or after agreement. The position is for 2 years.  

About the groups
The Choudhary lab is technically and internationally diverse and embedded in an excellent environment that supports high-quality research and encourages interdisciplinary collaboration. The Choudhary lab conducts experimental and computational research using interdisciplinary, state-of-the-art technologies, including quantitative proteomics, next-generation nucleic acid sequencing, advanced microscopy, CRISPR-based genome editing, and bioinformatics. The lab uses diverse cell models, including embryonic stem cells and their differentiated derivatives.

The Choudhary lab shares the laboratory space with the group of Prof. Matthias Mann and works closely with his group. The group extensively collaborates with top-level international researchers, routinely publishes in top-ranked journals, and has an outstanding track record in training the next generation of researchers. The major publications from the groups include Narita et al. https://www.biorxiv.org/content/10.1101/2022.07.18.500456v2, Narita et al. https://www.biorxiv.org/content/10.1101/2022.07.18.500459v2, Narita et al., Mol Cell. 2021, Narita et al. Nat Rev Mol Cell Biol 2019; Weinert and Narita et al., Cell 2018; Gupta et al., Cell 2018; Scholz et al., Nat Biotech 2015; Weinert et al., Mol Cell 2013; Povlsen and Beli et al., Nat Cell Biol 2012; and Beli et al. Mol Cell 2012.

We are now looking for enthusiastic candidates with a PhD and/or MD (i.e. level of education corresponding to the Danish PhD degree).

Project description
Our group works in the broad area of proteomics, genomics, and cell signaling. In the envisioned projects, we aim to use quantitative proteomics to further uncover the proteome-wide scope, dynamics, and enzymatic regulation of lysine acetylation and ubiquitylation. We are also interested in combining CRISPR-based genome editing with NGS-based approaches (i.e. RNA-seq, ChIP-seq, ATAC-seq) and cell biological approaches to uncover new regulatory pathways and decipher underlying mechanisms.

Depending on the candidate´s background, the postdoc candidate will either perform wet laboratory experiments involving cultured mammalian cells, CRISPR, and NGS-based genomic technologies, or proteomics technologies to generate large-scale datasets and to understand cellular regulatory mechanisms. Candidate with interest in data analysis is expected to perform bioinformatic analyses of next-generation sequencing data, including ChIP-seq, RNA-seq, Nascent-seq, and ATAC-seq. The candidates with experience in both wet lab and bioinformatics will be able to do both (i.e., work in the wet lab and perform bioinformatics analyses). If you would like to know more about the project(s), please contact us!

Qualifications
The candidate should have demonstrated excellent scientific productivity, evidenced by high-quality research publications, be able to conduct independent and creative research, and show good interpersonal and communication skills.

  • The candidate is required to have a PhD/MD level of education corresponding to the Danish PhD degree in natural or medical science.
  • Excellent scientific track record, including at least one publication in a high-quality, peer-reviewed international journal. Pre-prints can be counted for fulfilling this requirement.
  • Expert knowledge in one or more of the following areas is advantageous:
  1. Experience in molecular biology techniques, including proficient use of CRISPR-based genome editing
  2. Prior experience in the area of epigenetics, and gene transcription regulation.
  3. Hands-on experience in generating datasets for ChIP-seq, RNA-seq, ATAC-seq
  4. Hands-on experience in quantitative mass spectrometry for analyzing proteins, their modifications, and protein-protein interactions
  5. Hands-on experience in bioinformatic analyzing next-generation sequencing datasets, such as ChIP-seq, RNA-seq, ATAC-seq
  6. Experience in computer programming languages, such as R, Python
    Strong background in the statistical analysis of large-scale data
  • Good communication skills, both oral and written.
  • An analytical aptitude for devising innovative scientific or technical solutions.

For further information, please contact Professor Chuna Ram Choudhary, email: chuna.choudhary@cpr.ku.dk.

Place of employment and work
The employment is at CPR (www.cpr.ku.dk), University of Copenhagen, located in central Copenhagen. In the past 10 years, CPR has established itself as a top-level research institute in protein signaling and network biology research. The research environment at CPR is ambitious and international, with approx. 30 different nationalities are currently represented. The Center comprises modern laboratories, supercomputer resources, and state-of-the-art research facilities. Seminars with high-profile international speakers and regular internal research seminars are organized at the Center. Denmark is often ranked as the happiest nation and Copenhagen is consistently ranked as one of the best cities for living. For more information on working and living in Denmark visit www.ism.ku.dk  (International staff mobility) and www.workingconditions.ku.dk.

Terms of salary and employment
The duration of the full-time position is 2 years. Tentative start date: 15 April 2023 or after agreement. The start date can be negotiated.

Salary, pension, and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization. Currently, the monthly salary starts at approx. 35,728 DKK / approx. 4,800 EUR (October 2022 level), plus 17.1 % in pension contribution. Depending on qualifications, a supplement may be negotiated.

The Danish Ministry of Finance and the Danish Confederation of Professional Associations (AC) have agreed on a protocol that makes it possible for all international researchers employed by the University to achieve a pension exemption, where the pension can be paid out as salary. For more information about the different pension schemes www.ism.ku.dk/onarrival/pension/.

Foreign and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

1. Cover letter

2. Curriculum vitae, incl. educational qualifications, experience, and a list of publications

3.  A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the degree is not yet awarded, it is sufficient to mention in the cover letter when the applicant expects to submit the thesis, and/or receive the qualifying degree

4. Names and contact details for 2-3 referees

Application deadline: 22 February 2023, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the above-mentioned requirements.

The further process
After the expiry of the application deadline, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at www.employment.ku.dk.

For further information about the position or the process or if you experience any technical difficulty with the online submission system, please contact SUND HR: sund-hr-cpr@sund.ku.dk

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.

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Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Contact

Chuna Ram Choudhary

Info

Application deadline: 22-02-2023
Employment start: 15-04-2023
Working hours: Full time
Department/Location: Novo Nordisk Foundation Center for Protein Research
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