Postdoc in Energy Homeostasis and Obesity Pathogenesis

Novo Nordisk Foundation Center for Basic Metabolic Research

Faculty of Health and Medical Sciences

University of Copenhagen

The University of Copenhagen is seeking a highly motivated and talented postdoctoral fellow to commence October 1, 2021 at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen.

The postdoctoral fellowship is part of the Novo Nordisk Foundation Center for Basic Metabolic Research International Postdoctoral Program www.cbmr.ku.dk/postdocprogram.

About us

The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010 and in 2017, we moved into new laboratories, offices and meeting rooms in the Maersk Tower www.maersktower.ku.dk.

The Center has around 240 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here www.cbmr.ku.dk.

Our research

The position available is in the Metabolism and Molecular Pharmacology Group headed by Associate Professor Christoffer Clemmensen. The Group studies the molecular and physiological underpinnings of energy homeostasis and behaviours linked to eating (e.g., see recent perspectives article). A closely related aim of our work is to develop new therapeutic strategies for the treatment of obesity and its metabolic co-morbidities. For this, we have established a diverse set of complementary experimental approaches, including dietary, genetic, surgical and pharmacological interventions in rodents. The rodent work is complemented by human intervention studies and cutting-edge medicinal chemistry and omics methods. You can read more about the Clemmensen Group here https://cbmr.ku.dk/research/nutrient-and-metabolite-sensing/clemmensen-group/.

Job description

The aim of this project is to identify and characterize new endocrine-like satiety signals that are secreted into circulation in response to experimental overfeeding in mice. We have established a mouse model of experimental overfeeding that enables us to dissect physiological and molecular defence mechanisms against overfeeding-induced weight gain. In close collaboration with the Schéele Group and the Deshmukh Group, the postdoctoral candidate will perform MS-based proteomics and peptidomics on tissues and media from cultured cells both obtained from animals undergoing experimental overfeeding. Following prediction of secreted factors and shortlisting of candidate signalling molecules, the next step is to functionally evaluate these in vivo and scrutinize effects on energy balance and animal behaviour. This research project heavily benefits from the unique interdisciplinary and collaborative culture at the Center.

Profile

The fellowship is aimed at early career researchers with a basic science background or clinicians who aspire to a career in academic medicine. We are particularly interested in candidates who are familiar with integrative research approaches within the broad area of basic metabolic research with an application towards human pathophysiology.

Required qualifications:

  • PhD in Biology or related sciences
  • Excellent scientific track record in relation to career stage
  • Strong background in rodent energy metabolism research
  • Profound experience with surgery in mice
  • Experience with mouse behavioural phenotyping is an advantage
  • Basic understanding of neuroscience and pharmacology is an advantage
  • Excellent English communication skills, both written and oral

Eligibility

The CBMR International Postdoctoral Program is open for applicants that hold a PhD degree awarded from a university outside of Denmark. The PhD degree has to be obtained before October 1, 2021. The program is also open for applicants with a Danish PhD degree who can document at least 12 months full-time research experience from outside Denmark. You are not eligible to apply for the program if you have been employed in a postdoctoral position for more than one year at the University of Copenhagen prior to the commencement of the fellowship.

Terms of employment

The employment as postdoc is a full time position for 3 years. Starting date is October 1, 2021.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

Questions

For further information about the position, please contact Associate Professor Christoffer Clemmensen at chc@sund.ku.dk. Questions regarding the CBMR International Postdoctoral Program must be directed to cbmr@sund.ku.dk. For questions regarding the recruitment procedure, please contact HR at sund-hr-cbmr@sund.ku.dk.

The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark. Read more at www.ism.ku.dk.

Application procedure

Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Cover letter expressing the motivation and previous research experience of the applicant (max 1 page)
  • Curriculum vitae
  • Copy of the PhD degree certificate and the Master degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor confirming it will be obtained before October 1, 2021 is acceptable
  • List of publications
  • References (name and contact details of at least two references)

Application Deadline: April 19, 2021, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.

The applicant will be assessed according to the Ministerial Order no. 242 of March 13, 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal background

APPLY NOW

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Contact

Christoffer Clemmensen
E-mail: chc@sund.ku.dk

Info

Application deadline: 19-04-2021
Employment start: 01-10-2021
Working hours: Full time
Department/Location: Novo Nordisk Foundation Center for Basic Metabolic Research
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