Postdoc in Metabolic Single-Cell Genomics

Novo Nordisk Foundation Center for Basic Metabolic Research

University of Copenhagen

The University of Copenhagen seeks a highly motivated and talented postdoctoral fellow to commence October 1, 2020 at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.

The postdoctoral fellowship is part of the Novo Nordisk Foundation Center for Basic Metabolic Research International Postdoctoral Program www.cbmr.ku.dk/postdocprogram.

About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010, and in 2017 we moved into new laboratories, offices and meeting rooms in the Maersk Tower www.maersktower.ku.dk.

The Center has around 200 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.

Our Research
In the Pers Group we study cellular heterogeneity underlying human obesity and type 2 diabetes. Our goal is to understand how the brain regulates body weight and blood glucose levels and in particular to identify specific genes, biological pathways and cell types regulating metabolic homeostasis. To address this goal, we leverage combinations of single-cell transcriptomics and chromatin accessibility assays, in vivo mouse studies, large-scale human genetics datasets and computational data integration techniques. Our team is interdisciplinary (molecular biologists, mathematicians, computational biologists and neurobiologists), international (five nationalities), gender-balanced and maintains strong international alliances (Michael W. Schwartz, University of Seattle, USA; Martin Myers Jr., University of Michigan, USA; Cecilia Lindgren, University of Oxford, UK). For more information and links to recent publications please visit www.cbmr.ku.dk/research/human-genomics-and-metagenomics-in-metabolism/pers-group.

Job Description

Type 2 diabetes patients exhibit considerable heterogeneity with respect to their phenotypic presentations and treatment responses. To disentangle the contribution of individual tissues to disease heterogeneity, your task would be to combine relevant in-house human single-cell datasets with large-scale human genetic association data to identify subgroups of type 2 diabetes patients exhibiting distinct clinical characteristics.  You would work with state-of-the-art human single-cell profiling data, large-scale genetic association data, deeply phenotyped cohorts and extensive longitudinal Danish electronic health register data (in collaboration with co-PI Dr. Torben Hansen, CBMR) and machine-learning techniques (in collaboration with co-PI prof. Morten Mørup, Technical University of Denmark).

Profile

The fellowship is aimed at early career researchers with a basic science background, we are particularly interested in candidates who are able to work independently, while being capable of interacting well within a group, and familiar with integrative research approaches within the area of basic metabolic research.

The ideal candidate combines:

  • A PhD in human genetics, computational biology, molecular biology or related sciences
  • An excellent scientific track record with at least one relevant first-author publication
  • Profound knowledge of human genetics
  • Experience in transcriptomics and large-scale molecular profiling data analysis
  • Experience with programming and, ideally, machine learning techniques
  • Excellent English communication skills, both written and oral.

Eligibility

The CBMR International Postdoctoral Program is open for applicants that hold a PhD degree awarded from a university outside of Denmark. The program is also open for applicants with a Danish PhD degree who can document at least 12 months full-time research experience from outside Denmark. You are not eligible to apply for the program if you have been employed in a postdoctoral position for more than one year at the University of Copenhagen prior to the commencement of the fellowship.

Terms of Employment

The employment as postdoc is a full-time position for 3 years. Starting date is October 1, 2020. Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

Questions

For further information about the position, please contact Associate Professor Tune H. Pers at tune.pers@sund.ku.dk. Questions regarding the CBMR International Postdoctoral Program must be directed to cbmr@sund.ku.dk. For questions regarding the recruitment procedure, please contact HR at sund-hr-cbmr@sund.ku.dk.

The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark. Read more at www.ism.ku.dk.

Application Procedure

  • Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:
  • Cover letter expressing the motivation and previous research experience of the applicant (max 1 page)
  • Curriculum vitae
  • Copy of the PhD degree certificate and the Master degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor is acceptable.
  • List of publications
  • References (name and contact details of at least two references)

 Application Deadline: March 22, 2020, 23.59pm CET
 
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
 
The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
 
You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.
 
The applicant will be assessed according to the Ministerial Order no. 242 of March 13, 2012 on the Appointment of Academic Staff at Universities.
 
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal background.

APPLY NOW

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Contact

Tune H Pers

Info

Application deadline: 22-03-2020
Employment start: 01-10-2020
Working hours: Full time
Department/Location: Novo Nordisk Foundation Center for Basic Metabolic Research

Search all vacancies