Postdoc in Genomics Discovery and Epidemiology
Novo Nordisk Foundation Center for Basic Metabolic Research
University of Copenhagen
The University of Copenhagen seeks a highly motivated and talented postdoctoral fellow to commence October 1, 2020 at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.
The postdoctoral fellowship is part of the Novo Nordisk Foundation Center for Basic Metabolic Research International Postdoctoral Program www.cbmr.ku.dk/postdocprogram.
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010, and in 2017 we moved into new laboratories, offices and meeting rooms in the Maersk Tower www.maersktower.ku.dk.
The Center has around 200 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.
The postdoc position is in the Genomics Discovery and Epidemiology Group, headed by Associate Professor Tuomas Kilpeläinen. The research group utilizes a range of epidemiological, bioinformatics and experimental tools to understand how genetic variation contributes to obesity and related metabolic disorders and to translate the genetic findings into preventive and therapeutic action. The group is international and diverse, including both clinically and computationally-oriented scientists with complementary expertise that bridges between basic and translational research. The group collaborates actively with local and international collaborators and is well-networked within international genetics consortia. You can read more about the Kilpeläinen Group at www.cbmr.ku.dk/research/human-genomics-and-metagenomics-in-metabolism/kilpelainen-group/
Insulin resistance and increased risk of type 2 diabetes are closely linked to obesity, but there is wide individual variability in the metabolic tolerance for carrying excess body fat. Recent studies have shown that multiple genetic loci are associated with higher insulin resistance but, paradoxically, lower levels of gluteofemoral fat, which appears to play a key role in the development of insulin resistance. However, the current understanding of the biological mechanisms that mediate the genetic relationship between lower gluteofemoral fat and higher insulin resistance remains limited. In the present research project, we strive to understand these mechanisms by a combination of in silico computational approaches and experimental studies guided by the in silico analyses. Your tasks will involve utilizing data from genome-wide association studies, large cohort studies, and other available data sources to examine the genetic relationship between gluteofemoral fat and insulin resistance. Your findings will also guide in vitro experimental studies that aim to identify gene enhancer regions mediating this relationship.
The fellowship is aimed at early career researchers with a basic science background or clinicians who aspire to a career in academic medicine. We are particularly interested in candidates who are familiar with integrative research approaches within the broad area of basic metabolic research with an application towards human pathophysiology.
- PhD in Biology, Biochemistry, Molecular Biology, Molecular Biomedicine, or related sciences
- Excellent scientific track record in relation to career stage
- Experience in epidemiological research
- Experience with statistical programming (e.g. R, SAS)
- Experience in working with genomic or other omics data
- Strong interest in research on obesity and metabolic disorders
- Interest in co-supervising PhD fellows and MSc students
- Excellent English communication skills, both written and oral
The CBMR International Postdoctoral Program is open for applicants that hold a PhD degree awarded from a university outside of Denmark. The program is also open for applicants with a Danish PhD degree who can document at least 12 months full-time research experience from outside Denmark. You are not eligible to apply for the program if you have been employed in a postdoctoral position for more than one year at the University of Copenhagen prior to the commencement of the fellowship.
Terms of Employment
The employment as postdoc is a full-time position for 3 years. Starting date is October 1, 2020.
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
For further information about the position, please contact Associate Professor Tuomas Kilpeläinen, firstname.lastname@example.org. Questions regarding the CBMR International Postdoctoral Program must be directed to email@example.com. For questions regarding the recruitment procedure, please contact HR at firstname.lastname@example.org.
The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark. Read more at www.ism.ku.dk.
Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Cover letter expressing the motivation and previous research experience of the applicant (max 1 page)
- Curriculum vitae
- Copy of the PhD degree certificate and the Master degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor is acceptable.
- List of publications
- References (name and contact details of at least two references)
Application Deadline: March 22, 2020, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.
The applicant will be assessed according to the Ministerial Order no. 242 of March 13, 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal background.
Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.