The Sandelin group is looking to recruit a talented postdoctoral researcher
to our highly dynamic research group working in the interface of computational
biology and genomics. The position is part of two larger projects on i) how
stress transfers between mother and fetus during pregnancy and ii) analysis of
the effect of probiotics in tissue and organoid gut models. The 2.5 year
postdoc will start 1 April 2019 or as soon as possible thereafter.
Description of the scientific environment
The projects are collaborations between the Sandelin group at
Bioinformatics Centre, Department of Biology and BRIC, the Sørig Hougaard group
at the National Research Centre for the Working Environment (NRCWE), and the
Kim Jensen group at BRIC and Chr. Hansen, a world leading company in production
of live bacteria.
The Sandelin group is a high-profile joint computational/experimental group
focusing on gene regulation and transcriptomics. The Bioinformatics Centre
employs around 50 researchers and has many international connections to
high-profile groups. The groups are housed in the Biocenter in central
Copenhagen, Denmark, at University of Copenhagen.
The Sørig Hougaard group at NRCWE focuses on developmental toxicology,
working environment and in particular effects of particles and stress on
reproduction and pregnancy. NRCWE is located within biking distance of the
The Kim Jensen group at BRIC focuses on unraveling the molecular mechanisms
that control stem cell fate during development, tissue homeostasis and during
disease using state of the art technologies including various sequencing and
patient derived organoid models.
The postdoc will work on two projects:
i) Characterization on how acute stress induced in pregnant mothers
transfers from mother to fetus, and the molecular signaling molecules and
regulators that underlie this process. This will be done through a time series
analysis in pregnant mice on RNA and protein levels, coupled to state of the
art computational analysis, and parallel investigations of signaling molecules
in blood. Experiments will mostly be done by one PhD student and technicians at
NRCWE, while the postdoc advertised here will be primarily responsible for data
analysis; however, the postdoc, PhD student and technicians are expected to
work as a team.
ii) Analysis of massive RNA-seq data sets from tissue and gut organoids
subjected to probiotics treatment. This is a collaboration between University
of Copenhagen and Chr. Hansen A/S, the world’s largest producer of live
bacteria. This project involves five other experimental postdocs.
The successful candidate will work both at the Biocenter, University of
Copenhagen and at NFA.
The postdoc will have a joint affiliation with Department of Biology, BRIC,
NFA and Chr Hansen.
The position is available for a 2.5-year period and your key tasks as a
postdoc at SCIENCE are:
To manage and carry through your research project
Applicants must hold a PhD or equivalent in bioinformatics or a mathematical
discipline with a strong biological interest, and a substantial publication
record in high-quality international journals focused on the analysis of
genomics data. Candidates finishing their PhD before 1 March 2019 will also be
Although the focus will be on computational work, the candidate will be
working closely together with experimental scientists, and will be expected to
understand the experiments and underlying biology and fruitfully interact with
other specialists. Therefore,
Strong experience in analyzing high-throughput
sequencing data, in particular RNA-seq
Documented experience in statistical analyses of
such data, including expression analysis, as well as quality control and
Strong programming skills in Python and R, or
equivalents, and experience using linux/unix platforms
Excellent English skills
One or more first authorships in well-respected
bioinformatics or genomics journals
Experience in multivariate statistics, mass-spec data analysis, model
building, network, time course analysis and sequence analysis are strong
advantages. Similarly, experience/knowledge in microbiology, toxicology and/or
inflammatory response, reproduction and developmental programming of disease is
Terms of employment
The position is covered by the Memorandum on Job Structure for Academic
Terms of appointment and payment accord to the agreement between the
Ministry of Finance and The Danish Confederation of Professional Associations
on Academics in the State.
The starting salary is currently up to DKK 426.625 including annual
supplement (+ pension up to DKK 72.952). Negotiation for salary supplement is
The application, in English, must be submitted electronically by clicking
APPLY NOW below.
- Cover Letter, detailing your motivation and
background for applying for the position
- PhD and MSc Diplomas
- List of publications
- Full contact details (Name, address, telephone
& email) of 1-3 professional referees
- Two letters of
The University wishes our staff to reflect the diversity
of society and thus welcomes applications from all qualified candidates
regardless of personal background.
The deadline for applications is 1 March 2019.
After the expiry of the deadline for applications, the authorized
recruitment manager selects applicants for assessment on the advice of the
Interview Committee. Afterwards an assessment committee will be appointed to
evaluate the selected applications. The applicants will be notified of the
composition of the committee and the final selection of a successful candidate
will be made by the Head of Department, based on the recommendations of the
assessment committee and the interview committee.
The main criterion for selection will be the research potential of the
applicant and the above mentioned skills. You can read more about the
recruitment process at http://employment.ku.dk/faculty/recruitment-process/.
For specific information about the position, please contact the principal
supervisor, Professor Albin Sandelin, Department of Biology and BRIC,
email@example.com, Direct phone: +45 35 32 12 85