PhD followship in MS-based proteomics at the Novo Nordisk Foundation Center for Protein Research

A PhD fellowship is available in the Nielsen group at The Novo Nordisk Foundation Center for Protein Research (CPR – www.cpr.ku.dk). The Center has been established at the Faculty of Health and Medical Sciences, University of Copenhagen, to promote basic and applied discovery research on human proteins of medical relevance. The Center comprises a wide range of expertise and resources including proteomics, structural biology and characterization of disease mechanisms.

The Nielsen group is lead by Group Leader Dr. Michael L. Nielsen, and by joining our team, you will be part of a young and dynamic team consisting of international researchers. The Nielsen group focuses on developing novel proteomics methods & technologies for studying the cellular outcomes at a ‘systems-level’, with the aim to understand cellular phenotypes and diseases. To this end, we employ cutting-edge mass spectrometry (MS)-based technologies for unbiased identification and quantification of post-translational modifications (PTMs).

For more information about the research group, please visit: http://www.cpr.ku.dk/nielsen/.

Focus of the Project
The PhD fellow is expected to use the cutting-edge proteomic technologies developed in the Nielsen group for dynamic and temporal characterization of ADP-ribosylation in mammalian cell systems, and to perform biological follow-up experiments on novel and interesting findings derived from proteomic screens. ADP-ribosylation has emerged as a vital PTM in many cellular processes, including DNA damage, Chromosome organization, Translation, protein localization, and others.


The ideal candidate is expected to investigate the cellular roles of ADP-ribosylation in the DNA damage response, and should be able to conduct independent and creative research, demonstrate scientific productivity, and show good inter-personal and communication skills.

Qualifications 

  • Candidates are required to have a Master degree in biochemistry, molecular biology or similar prior to starting.
  • An analytical aptitude of devising innovative scientific or technical solutions.
  • Prior experience in research fields related to ADP-ribosylation and/or the DNA damage response would be a distinct advantage.
  • Knowledge in one or more of the following area(s) would be considered an advantage: genetics and cell biology, cell signaling, or chromatin biology.
  • Prior experience in high resolution mass spectrometry is not essential, but would be considered an advantage.
  • Knowledge in bioinformatics and large-scale data analysis, and skills in statistical computational environment such as R and Python will be considered a distinct advantage, but not a requirement.
  • Good communication skills, both oral and written.
  • Strong motivation and excellent scientific skills are essential.

Start date: Spring 2020.

Place of employment and work
The employment is at CPR (www.cpr.ku.dk), University of Copenhagen, located in central Copenhagen. The research environment at CPR is vibrant, ambitious, and international, with approx. 30 different nationalities currently represented. The Center comprises modern laboratories and state-of-the-art facilities within protein science. Seminars with high-profile international speakers and regular internal research seminars are organized at the Center.

Terms of salary and employment
The PhD fellowship is financially supported by the CPR and the Faculty of Health and Medical Sciences and is for a period of three years.


The research project will be carried out in collaboration with other groups at the center. The candidate must have equivalent to a Danish Master degree. It is a prerequisite that the candidate is successfully enrolled as a PhD fellow at the Graduate School of Faculty of Health and Medical Sciences, University of Copenhagen, in accordance to the provision of the Executive Order no. 18 of 14 January 2008 regarding the PhD degree.

The PhD fellowship must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins at DKK 27,362 / approx. EUR 3.648 (October 2019-level) plus an employer paid pension contribution.

The Danish Ministry of Finance and the Danish Confederation of Professional Associations (AC) have agreed on a protocol that makes it possible for all international researchers employed by the University to achieve a pension exemption, where the pension will be paid as salary. For more information about the different pension schemes: http://ism.ku.dk/onarrival/pension/.

Questions
For further information about the PhD fellowship, please contact Professor Michael Lund Nielsen by e-mail: michael.lund.nielsen@cpr.ku.dk.

General information about PhD study at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/.

Application procedure
Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format:  

  1. Motivated letter of application, including an outline for research projects of interest.
  2. Curriculum vitae, incl. education and experience
  3. List of publications
  4. Letters of recommendation
  5. Names and contact details for two referees

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

Application deadline: February 29, 2020, 23.59 p.m. CET.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The Faculty of Health and Medical Sciences comprises approximately 7800 students, 1550 PhD students and 4400 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.

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Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

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Michael Lund Nielsen

Info

Application deadline: 29-02-2020
Employment start: 01-05-2020
Department/Location: Novo Nordisk Foundation Center for Protein Research

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