Inferring patterns of natural selection and
complex trait evolution using ancient DNA
Department of Biology, Faculty of Science, at University of Copenhagen invites
applications for a postdoctoral fellow position at the University of Copenhagen,
in the research group of Fernando Racimo. The Racimo group focuses on using
ancient and present-day genomes to understand patterns of selection and
admixture over time, and to develop methods to jointly analyze population and
functional genomic data. We are particularly interested in human evolution, on
both an ancient scale (i.e. modeling the joint history of Neanderthals,
Denisovans and modern humans) and a recent scale (i.e. finding functional
variants that were selected in humans during major cultural transitions, like
the advent of agriculture).
position is to be filled by April 1st, 2019, or as soon as possible
candidate will be able to work with unprecedentedly large ancient genomic
dataset from a period spanning the last 50,000 years of human history, in
combination with functional datasets and medical biobanks. The focus of the
project will be on integrating ancient genomics with population genetic theory
and quantitative genetic resources, to learn about how humans adapted to their
environments as they expanded across the globe, with a particular focus on complex
candidate will have freedom to design their project in consultation with the
advisor, and the project can range from theoretical methods development to
empirical data analysis. Research topics can include: 1) Utilizing trait-association
data from metabolic, neurological and anthropometric studies to learn about the
evolution of complex traits in ancient genomes from the Paleolithic, Neolithic,
Bronze Age and Iron Age; 2) Developing methods to detect genes under positive
selection when working with multiple populations related to each other in
complex ways; 3) Searching for functional variants that were positively
selected in humans over time during major cultural transitions, like the advent
of agriculture; 4) Testing among different models of evolution on
trait-associated variants over time.
candidate will work at the Lundbeck GeoGenetics Centre, a world-leading
institution in ancient DNA studies. The position is
for 3 years, and is fully funded. The candidate will have to opportunity
to collaborate with leaders in the fields of paleogenomics, population genetics
and quantitative genetics, like Eske Willerslev, Rasmus Nielsen, Martin Sikora
and Morten Allentoft. The University of
Copenhagen is ranked the 29th best university in the world according
to Academic Ranking of World Universities 2018 (http://www.shanghairanking.com/ARWU2018.html).
It provides excellent academic programs in biology, statistics, computer
science and mathematics. The GeoGenetics Centre is located in central
Copenhagen, Denmark – a city that is ranked among the most liveable cities in
the world (see e.g. https://placebrandobserver.com/monocle-quality-of-life-survey-25-most-liveable-cities-2018/
candidate will have a MD, PhD, or equivalent doctorate, with a strong
background in one or more of the following areas: population genetics, human
genetics, genomics, computational biology, bioinformatics, machine learning,
data science, mathematics and/or statistics. The ideal candidate will
demonstrate a working proficiency in programming and statistical computing
(e.g. experience in Python, R, C/C++, Java or Julia) and have experience
handling large data sets in the UNIX operating environment.
Salary and terms of employment
The position is
covered by the Memorandum on Job Structure for Academic Staff.
appointment and payment accord to the agreement between the Ministry of
Finance and The Danish Confederation of Professional Associations on Academics
in the State.
salary is currently up to DKK 426.625 including annual supplement (+ pension up
to DKK 72.952). Negotiation for salary supplement is possible.
in English, must be submitted electronically by clicking APPLY NOW below.
- A cover letter (max.
one page) describing your background, personal qualities, research interests
and specific reasons for applying to this position.
- Diplomas (PhD degree
- Description of
- Complete publication
- Contact details of
two people for references
consider applying from abroad, you may find useful information on how it is to
work in Denmark and at UCPH in this links:
The University of Copenhagen wishes to reflect the diversity of society and
welcome applications from all qualified candidates regardless of age,
disability, gender, nationality, race, religion or sexual orientation.
Appointment will be based on merit alone.
The deadline for applications is 28 Feb
2019, 23:59 GMT +1.
Part of the International Alliance of Research Universities (IARU), and
among Europe's top-ranking universities,
the University of Copenhagen promotes research and teaching of the highest
international standard. Rich in tradition and modern in outlook, the University
gives students and staff the opportunity to cultivate their talent in an
ambitious and informal environment. An effective organization - with good
working conditions and a collaborative work culture - creates the ideal
framework for a successful academic career.
further information please contact Assist. Prof. Fernando Racimo: email@example.com
Professor in Population Genetics
Foundation GeoGenetics Centre
will be held on 14 March 2019.