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PhD fellow for bioinformatics analysis of cardiac proteomics data

Description
We are seeking a PhD fellow to become part of the Cardiac Proteomics group led by Associate Professor Alicia Lundby at the Department of Biomedical Sciences and the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen, Denmark.

In the Cardiac Proteomics group we perform high-resolution LC-MS/MS based investigations of cardiac tissue biopsies to obtain insights on protein expression in the heart beyond the current molecular understanding of the heart. We work with cardiologists to ensure a research focus on the most relevant human cardiac biopsies, and when necessary, we investigate cardiac tissue from model organisms. In addition to the experimental proteomics based research we collaborate with world-leading geneticists, which allows us to always ensure relevance of our research to human cardiac diseases. We are now embarking on an analysis to profile the cardiac protein expression landscape across humans as well as model organisms to form a foundation for improved target discovery for cardiac disease intervention. To this end we are seeking a data scientist to analyze substantial proteomics data from hearts collected in the Cardiac Proteomics group.

Responsibilities And Tasks
The successful candidate will be working in a team of scientists across multiple scientific fields focused on improving our molecular understanding of cardiac pathophysiologies. The candidate will work closely with experimental biologists, bioinformaticians and geneticists to solve fundamental challenges in cardiac research. The position will be ideally suited to a person that has obtained a Master’s degree or similar and is interested in pursuing a career in research. The position provides an opportunity to develop expertise in quantitative mass spectrometry, a cutting-edge technology and a powerful tool for discovery. Previous research experience is a requirement.


The PhD Position Could Cover

  • Unbiased data-driven analysis of large-scale proteomics data sets of cardiac protein expression profiles from humans and model organisms
  • Large scale data integration of proteomics data with matched genetic datasets
  • Bioinformatical pathway and pattern recognition analyses
  • Design of specific experimental follow-up studies to test hypotheses generated from analysis


Qualifications

  • Candidates should have a Master’s degree or equivalent.
  • Ability and enthusiasm to learn new methods/techniques
  • Good communication skills in English, both oral and written
  • An interest in computational work and familiarity with programming in programs such as python, C++ or R

Overall a preferred applicant has an excellent academic track record, solid research experience and is highly motivated deploying bioinformatics analyses to extract novel findings of importance to cardiac (patho)physiology.

The Candidate Should

  • Have a proven track record within the fields of bioinformatics, proteomics or big data analysis
  • Have demonstrated early in his/her career a capacity for excellence
  • Make this position his/her number one priority
  • Have a genuine interest in science
  • Have a strong work ethics
  • Be a team player

We offer
We offer an interesting and challenging job in an international environment focusing on cardiac research. You will become part of a research environment spanning cardiologists, geneticists performing next generation sequencing on cardiac patient samples, experimental groups performing follow-up experiments in model organisms such as zebrafish, mouse and pig as well as molecular biologists. We strive for academic excellence, collegial respect and freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Confederation of Professional Associations (AC). The allowance will be agreed with the relevant union.

Workplace and period of employment
Workplace is located at The Panum Institute, University of Copenhagen, Denmark.
The period of employment is 3 years.

Further information
Further information may be obtained from Associate Professor Alicia Lundby: alicia.lundby@sund.ku.dk. For administrative questions, please contact Ragnhild Mostert; rmostert@sund.ku.dk

You can read more about Center for Protein Research at www.cpr.ku.dk

You can read more about Cardiac Proteomics Group at http://www.ionchannel.ku.dk/research/proteomics/

Application procedure
Please submit your online application by clicking “apply now” below no later than  1 June 2017.

The File Must Include
Applications must be submitted as one PDF file containing all materials to be given consideration. Attach all your materials in English in one PDF file. The application should contain:

  • Application (cover letter)
  • CV
  • Diploma (an official translation into English)
  • List of publications

Applications and enclosures received after the deadline will not be considered.

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at www.employment.ku.dk


All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

General information about PhD programs at the Faculty of Health and Medical Sciences is available at the Graduate School’s website

 

 The Faculty of Health and Medical Sciences comprises approximately 7500 students, 1500 PhD students and 3200 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community.




 

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Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Contact

Alicia Lundby

Info

Application deadline: 01-06-2017
Employment type: Limited period
Employment start: 01-08-2017
Department/Location: Dept. of Biomedical Sciences

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