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PhD scholarship at Center for Translational Neuromedicine

 

Center for Translational Neuromedicine, University of Copenhagen, is looking for a highly motivated PhD fellow. This position offers the opportunity to work in a collaborative multi-disciplinary team engaged in research in Huntington’s disease.

Project description

Historically, the study of Huntington’s disease (HD) has focused on medium spiny neuron degeneration, yet recent advancements have been steadily shifting the paradigm, revealing glial cells as key contributors to the genesis and progression of HD. Our most recent findings argue that this is largely due to a mutant huntingtin dependent impairment of human glial progenitor cell (hGPC) differentiation. This raises the possibility of hGPC replacement as a novel therapeutic strategy for HD. However, whether healthy hGPCs have the biological capacity to outcompete and replace their diseased counterparts remains unknown. Thus, this PhD project will focus on the characterization the competitive interactions between normal and HD hGPCs and the assessment of the therapeutic potential of hGPC transplantation in HD using our human glial chimeric mouse model. This study is expected to provide the basis for future clinical trials.

 

 The key tasks as a PhD fellow in CTN are to:

  • Carry out and complete an independent research project under supervision

  • Write scientific articles and the PhD thesis on the grounds of your research project

  • Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points

  • Obtain experience with teaching and/or other types of dissemination related to your PhD project

  • Participate in national and international congresses and scientific meetings

  • Obtain experience from an external research institution, preferably abroad

Further information on the Center can be found at http://ctn.ku.dk/. Inquiries about the position can be made to Administrator Ann Christensen, ann.christensen@sund.ku.dk.

The position is a full-time position and is open from 1st of January 2018.

Qualifications

  • Candidates for the PhD position must hold a Master’s degree in biomedical research or related fields (previous training in neurobiology is highly beneficial).

  • At least one year of competent laboratory experience enabling the candidate to execute independent laboratory work.

  • The successful candidate is not expected to have all the skills listed at the start of employment but experience in stem cell culture and their differentiation into different glial lineages, molecular biology and mammalian genome editing will be considered as an advantage. The candidate is expected to train to obtain competency in above skills at a reasonable and rapid pace. Dedication to outlined research protocols is necessary.

  • The successful candidate should be organized, self-motivated, result-oriented and capable of working independently in a collaborative setting.

  • The successful candidate will possess strong written and oral communication skills with the ability to readily learn new experimental techniques. Strong analytical, communication, organizational and computer skills are also required.

Terms of employment

The successful candidate will be offered a full-time 3-year position. The position is covered by the Memorandum on Job Structure for Academic Staff.

Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.

Please include

  • Curriculum vitae

  • Diplomas (Master, PhD or equivalent)

  • A motivation letter. Prior example(s) illustrating your drive and/or abilities, that would be pertinent to the position, is appreciated

  • List of publications

  • The contact information of 2-3 referees

The deadline for applications is 24th of November 2017.

Application procedure

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

 

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Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Contact

Ann Lee Berger Christensen

Info

Application deadline: 24-11-2017
Employment start: 01-01-2018
Working hours: Full time
Department/Location: Center for Translational Neuromedicine

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