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PhD fellowship on “Improving CRISPR genome editing efficiency by modifying epigenetic marks” at Copenhagen Center for Glycomics

PhD fellowship on “Improving CRISPR genome editing efficiency by modifying epigenetic marks” at Copenhagen Center for Glycomics at The Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen  
 
Copenhagen Center for Glycomics invites applicants for one or more 3-year EC Marie Sklodowska-Curie PhD fellowships in the research area of glycobiology. The fellowships are available from March 1st, 2018 or as soon as possible thereafter.  
 
Job description 
 
The main objective of the project is to improve CRISPR genome editing efficiency of human cells. We will develop and use different strategies to improve current editing strategies, including the identification and alteration of DNA repair candidate genes. The improved methods will be tested on preclinical 3D tissue models mimicking human disease. We are looking for a highly motivated and enthusiastic candidate with the following qualifications: 
 
  • A Master of Science in biochemistry, molecular biology, biology, medicine or similar 
  • Experience in cell-culture work, molecular biology, and genetic engineering techniques is an advantage 
  • Excellent communication skills in English an advantage  
 
Your key tasks:
 
  • Carry out independent research under supervision 
  • Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points 
  • Participate in active research environments  
  • An obligation to conduct some undergraduate teaching and associated examinations or other types of dissemination related to your PhD project 
  • Write a PhD thesis on the grounds of your project 
 
The project will be supervised by professor Hans Wandall and associate professors Eric P. Bennett. 
 
Scientific environment 
 
Copenhagen Center for Glycomics is a Center of Excellence funded partly by the Danish National Research Foundation (DNRF). The Center is comprised of 6 senior professors, 6 junior professors, 5 post docs and 11 PhD students, and focuses on complex carbohydrates and their role in health and disease. We have a unique approach to glycomics using primarily gene editing of the glycogenome to uncover and dissect biological functions of glycosylation.
 
The Department of Cellular and Molecular Medicine (ICMM) offers an ambitious scientific environment, with many different nationalities represented. ICMM aims to produce research with high international impact focusing on the functional cell, its genetic components and molecular cellular mechanisms in a medical context. ICMM currently comprises five research programmes, three high profile Research Centers as well as a number of international research groups. The scientists at ICMM are involved in high quality research based undergraduate and graduate teaching programs at the University of Copenhagen. You can read more at www.icmm.ku.dk  
 
Required qualifications  
 
1. Early-stage researchers (ESR) are those who, at the time of recruitment by the University of Copenhagen, are in the first four years (full-time equivalent) of their research careers. This is measured from the date when they obtained the degree which formally entitles them to embark on a doctorate, either in the country in which the degree was obtained or in the country in which the research training is provided, irrespective of whether or not a doctorate was envisaged. Please note that applicants cannot already hold a PhD at the time of recruitment. 
 
2. Conditions of international mobility of researchers: The early-stage researchers are required to undertake transnational mobility (i.e. move from one country to another) when taking up the appointment.  ESRs must not have resided or carried out their main activity (work, studies, etc.) in the country of their host organisation for more than 12 months in the 3 years immediately prior to their recruitment. Short stays, such as holidays, are not taken into account. 
 
Terms of employment:
  
The successful PhD candidate will be offered a full-time position for a period of three years, contingent on a satisfactory performance, with the specific intent that it results in a PhD degree and scientific publications.  
 
It is a prerequisite for the appointment as a PhD fellow that the person concerned can be registered as a PhD fellow according to the Ministry of Science, Technology and Innovation Executive Order no 18 of 14. January 2008. Information about the PhD programs at the Faculty of Health Science can be found at healthscience.ku.dk/phd/. 
 
Salary and other terms and conditions of appointment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant professional organization.  
 
Questions 
For further information about the fellowship please contact: Hans Wandall (hhw@sund.ku.dk) 
 
Foreign applicants may find the following links useful: www.ism.ku.dk  (International Staff Mobility) and www.workingconditions.ku.dk.
 
Application procedure 
 
The application must be submitted electronically by clicking APPLY NOW below
.  
Applications must be written in English and include (i) a motivation for the application (up to 1 A4 page), (ii) curriculum vitae, (iii) list of publications, (iv) a copy of MSc diploma and grade transcripts, (v) a short review of scientific research conducted previously for an MSc thesis or equivalent, (vi) the names, e-mails, telephone numbers and addresses of 2-3 referees. 
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application will be has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk    
 
The deadline for applications is November 15th, 2017. Applications received later than this date will not be considered.
 
Founded in 1479, the University of Copenhagen is the oldest university in Denmark. With 37,000 students and 9,000 employees, it is among the largest universities in Scandinavia and one of the highest ranking in Europe. The University consists of six faculties, which cover Health and Medical Sciences, Humanities, Law, Science, Social Sciences and Theology 
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Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Info

Application deadline: 15-11-2017
Employment start: 01-03-2018
Working hours: Full time
Department/Location: ICMM

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