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PhD stipend in protein kinase A regulation

A time-limited 3-year PhD position at Section for Molecular and Cellular Neuroscience, Center for Neuroscience is availble as soon as possible. The aim of the project is to investigate the role of PICK1 and novel natural compound to regulate PKA activity and function in cells and tissue.

 

The PhD student will study have the interaction with PICK1, recently identified in the group, regulate the activity and function of PKA in HEK293 cells as well as in synaptic plasticity in hippocampus and dense core vesicle biogenesis in endocrine tissue. Furthermore the project will aim to characterize newly discovered diterpenoids (similar to foskolin) from natural sources and direct/validate production through synthetic biology.

 

The studies will among others involve pharmacological assays, live microscopy of FRET based biosensors, ex vivo biochemical analyses as well as eletrophysiological charaterization and in vivo studies of knock in mice.

 

In connection with the appointment to the post, special importance will be attached to the applicant having the following professional and personal qualifications:

 

  • A Master’s degree in biochemistry, molecular biomedicine, human biology or in an equivalent area, preferable from an internationally recognized university.
  • Experience with molecular biology
  • Experience with pharmacological assays
  • Experience with confocal live microscopy and immunostainings
  • Experience with ex vivo biochemistry (phosphor-assays and Co-IP)
  • Experience with in vivo mouse models
  • Excellent communication skills, both written and oral englis

 

All highly motivated and ambitious candidates, regardless of their personal background and status, are encouraged to apply.

 

The position is offered for a period of three years and employment is governed by the Protocol on PhD Research Fellows signed by the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations). In addition to research activities, the PhD candidate will be expected – during the period of the stipend – to acquire experience in teaching and/or other types of presentations.

 

For further information, please contact Professor Ulrik Gether, e-mail: gether@sund.ku.dk

You can apply by clicking Apply Now below.

 

The application must include following appendices:

  • A letter of motivation

  • A current curriculum vitae

  • Copies of relevant diplomas

  • A complete list of publications (if any)

 

The deadline for applications is July 28th 2017. Any applications received after this time will not be considered.

 

Application procedure

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk 

 

The University of Copenhagen wishes to encourage everyone interested in this post to apply, regardless of personal background

 

The University of Copenhagen actively influences current and future generations through excellent research, education and co-operation. UCPH is one of the highest ranked universities in Europe and is Denmark’s oldest university, founded in 1479. Today, the University has 37,000 students and 9,000 employees affiliated across six faculties: humanities, law, natural sciences, social sciences, health sciences and theology. www.ku.dk/english/.


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Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

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Ulrik Gether

Info

Application deadline: 28-07-2017
Employment start: Start as soon as possible
Working hours: Full time
Department/Location: Center for Neuroscience

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