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Postdoc in Human Pluripotent Stem Cell-based Cell Therapy in Type 1 Diabetes at the Novo Nordisk Foundation Center for Stem Cell Biology (DanStem)

Background:  
The Novo Nordisk Foundation Center for Stem Cell Biology – DanStem has been established as a result of a series of international recruitments coupled with internationally recognized research groups focused on insulin producing beta cells and cancer research already located at the University of Copenhagen. DanStem addresses basic research questions in stem cell and developmental biology and has activities focused on the translation of promising basic research results into new strategies and targets for the development of new therapies for cancer and chronic diseases such as diabetes and liver failure.
 
Find more information about the Center at http://danstem.ku.dk/
 
The goal of this project is to engineer therapeutically active islet-like aggregates for future cell therapy phase 1 trials in Type 1 Diabetes (T1D).  
 
Job Description:  
We are looking for a postdoctoral candidate with a strong cell biological and cell signaling background in directed differentiation of human pluripotent stem cell biology. Experience in differentiation towards pancreatic lineages is a merit. The candidate is expected to work on the engineering of human pluripotent stem cell-derived islet of Langerhans-like aggregates with functional properties close to human islets. The functionality and therapeutic potential of the aggregates will be tested in vitro and in vivo in mice. The candidate is expected to use state-of-the-art genetics, molecular and cell biological, and tissue engineering experimental strategies. The candidate will work together with a dedicated team of scientists and technicians who together will tackle bottle-necks towards implementing the phase 1 clinical trials in T1D.  
 
Qualifications:  
The candidate is required to hold a PhD degree in pluripotent stem cell/developmental biology. A few years of postdoctoral experience in the same areas is a merit. The candidate should also have hands on experience in human pluripotent stem cell maintenance and differentiation, 3D culture of pluripotent stem cells, various cell and molecular biological methods, flow cytometry and live-cell imaging. Finally, we are looking for applicants with a good record of peer reviewed scientific publications, grant writing skills and an interest in team work.  
 
Employment Conditions:  
The position is for 2 years with a possible extension. The employment is planned to start as soon as possible or upon agreement with the chosen candidate.  
 
The terms of employment are set according to the Agreement between the Ministry of Finance and The Danish Confederation of Professional Associations or other relevant professional organization. The position will be at the level of postdoctoral fellow and the basic salary according to seniority is 32.700-34.400 DKK/month. A supplement could be negotiated, dependent on the candidate´s experiences and qualifications. In addition, a monthly contribution of 17.1% of the salary is paid into a pension fund.  
 
Applicants recruited from abroad may be eligible for a special researcher taxation scheme. In all cases, the ability to perform the job will be the primary consideration, and thus we encourage all - regardless of their personal background and status - to apply.  
 
For further information contact Professor Henrik Semb, Henrik.semb@sund.ku.dk  
 
International applicants may find the following links useful: UCHP’s international dept. ISM on http://ism.ku.dk/  and Work In Denmark on https://www.workindenmark.dk/  
 
Application instruction:  
The application must be submitted online and in English, by clicking on “Apply online” below.  
 
The closing date for applications is 23.59pm, November 1st 2017.  
 
The application must include:
  • Cover letter detailing the basis on which the applicant scientific qualifications meet the requirements for this position.  
  • Curriculum vitae.  
  • List of references (full address, incl. email and phone number)  
  • Diplomas – all relevant certificates.  
  • List of publications.  
Application procedure:  
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on his/her assessment. You may read about the recruitment process on http://employment.ku.dk/faculty/recruitment-process
 
DanStem and The University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates, regardless of personal background.  
 
Founded in 1479, the University of Copenhagen is the oldest university in Denmark. With 37,000 students and 9,000 employees, it is among the largest universities in Scandinavia and one of the highest ranking in Europe. The University consists of six faculties, which cover Health and Medical Sciences, Humanities, Law, Science, Social Sciences and Theology.  
 
 
 
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Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Info

Application deadline: 01-11-2017
Employment start: 01-12-2017
Working hours: Full time
Department/Location: DanStem

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