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A Postdoctoral position in computational biology

A Postdoctoral position in computational biology


A postdoctoral stipend is available in the clinical proteomics group at The Novo Nordisk Foundation Center for Protein Research (CPR – www.cpr.ku.dk). The Center has been established at the Faculty of Health and Medical Sciences, University of Copenhagen, to promote basic and applied discovery research on human proteins of medical relevance. The Center comprises a wide range of expertise and resources including proteomics, protein production and characterization in disease mechanisms. The clinical proteomics group is led by Prof. Dr. Matthias Mann, a leading authority in mass spectrometry-based proteomics with more than 180,000 citations and an h-factor of 199 (Google Scholar).  

The clinical proteomics group develops and applies proteomics technology with a goal of understanding health and disease and making an impact in public health. We work in close synergy with the Proteomics and Cell Signaling group at the Max-Planck Institute of Biochemistry in Munich, which is also led by Prof. Mann as well as other groups at the CPR, especially Prof. Chunaram Choudhary in cell signaling and Prof. Søren Brunak in bioinformatics and patient record mining.

Our particular focus is on the plasma proteome in the context of metabolic disorders such as diabetes. To this end, we are developing technology for the rapid and large scale analysis of plasma proteomes using mass spectrometry-based proteomics to a depth of at least 1000 proteins per patient. We have termed this approach ‘plasma proteome profiling’ and our goal is to develop it into a comprehensive tool for medical diagnostics (Philip Geyer et al, Cell Systems 2016). We are currently looking for a talented and motivated post-doctoral fellow with experience in computational biology to join a young and dynamic team in beautiful Copenhagen.

For more information about the research group please visit:

http://www.cpr.ku.dk/research/proteomics/mann-group/

Project Description

The clinical proteomics group was established with a generous grant from the Novo-Nordisk Foundation in December 2015. At this point, we have developed part of the technology required for deep plasma proteomics and we have started to apply this technology to small and medium scale clinical studies. Characterizing the plasma proteome in metabolic diseases such as diabetes and life style (diet and exercise) are current priorities. Longer term we have many other interests such as applying the technology in the context of patient stratification, assessing the efficacy of intervention, developing biomarkers in neurodegenerative diseases, to name just a few.

The successful candidate should be able to contribute to the development and application of new computational tools that use large scale proteomics (or other omics datasets) to increase our knowledge of biology and to advance the diagnosis, treatment or prevention of diseases. He or she should be able to develop new and innovative (multi) omics modeling or visualization methods that make the results of omics datasets accessible to research scientist or clinicians. The candidate is also expected to work in close collaborations with Prof. Søren Brunak’s group at CPR. 

Projected start date: Autumn 2017

Qualifications

  • The candidate is required to have a PhD or equivalent degree in the natural, computational or medical science.
  • Excellent scientific track record, including at least one publication as first author in a high quality, peer reviewed international journal.
  • A good molecular and computational biology/molecular biomedicine background is required.
  • Programming skills are required, preferably in languages such as Python and/or R.
  • Demonstrable experience with integration and analysis of multi–omics data is required.
  • Experience with analysis of proteomics data would be considered a distinct advantage.
  • Prior experience with network biology is highly desirable. The candidate needs to be able to work effectively in an international and multidisciplinary team.
  • Demonstrated writing and other communication skills are advantageous.

Place of employment and work

The employment is at CPR (www.cpr.ku.dk), University of Copenhagen, located in central Copenhagen. The research environment at CPR is vibrant and ambitious but also supportive. Currently about 30 different nationalities are represented. The Center comprises modern laboratories and state-of-the-art facilities in protein science and related areas. The institute regularly organizes seminars with high-profile international speakers as well as other events.

Terms of salary and employment

Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization. Currently, the monthly salary is around 32,350 – 34,060 DKK (around 4,250€) plus 17.1 % in pension contribution. The position will be 2-3 years.

Application

Please submit your application electronically via the APPLY NOW button below. 

Your application should include the following documents:

  • Letter of motivation for the application
  • Curriculum vitae, incl. education and experience
  • List of publications
  • Letters of recommendation
  • Names and contact details for at least two referees

 For further information about the position, please contact CPR:

Jobs@cpr.ku.dk 

Deadline for application: 27 May 2017

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk    


APPLY NOW

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Contact

Matthias Mann
E-mail: jobs@cpr.ku.dk

Info

Application deadline: 27-05-2017
Employment type: Limited period
Employment start: 01-09-2017
Department/Location: Center for Protein Research

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