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PhD fellow in non-coding Transcription

PhD fellow in non-coding Transcription
Copenhagen Plant Science Centre
Department of Plant and Environmental Sciences
Faculty of Science
University of Copenhagen

Copenhagen Plant Science Centre (CPSC) at the Department of Plant and Environmental Sciences, Faculty of Science at University of Copenhagen is seeking a candidate for a 3-year PhD-scholarship commencing 1 September 2017 or as soon as possible thereafter.

Project description
The Marquardt lab is interested in understanding the functional significance of abundant yet mysterious non-coding sequences present in genomes. We employ cutting edge budding yeast technology to identify the molecular mechanisms controlling transcription of non-coding sequences into long non-coding RNA (lncRNA). We disrupt these regulatory mechanisms in higher organisms such as Arabidopsis to study the functional roles of non-coding transcription in environmental responses.  

We are looking for a PhD student enthusiastic about lncRNA transcription. Your main project will be to identify novel pathways controlling divergent non-coding transcription from gene promoters. You will develop and apply high-throughput genomics approaches to identify novel players. Further molecular characterization of these pathways will enable you to study the function of divergent long non-coding transcription in yeast, plant and human. The project is inter-disciplinary; you will work at the interface of the research areas: Chromatin Biology, Pol II Transcription and Non-Coding RNA. Your enthusiasm will help you to develop a current molecular understanding of these fields to push the boundaries of current knowledge.

Principal supervisor is Sebastian Marquardt, Department of Plant and Environmental Sciences, email: sebastian.marquardt@plen.ku.dk

Job description
The position is available for a 3-year period and your key tasks as a PhD student at SCIENCE are:

  • Manage and carry through your research project
  • Take PhD courses
  • Write scientific articles and your PhD thesis
  • Participate in scientific meetings
  • Stay at an external research institution for a few months, preferably abroad
  • Teach and disseminate your research.

Key criteria for the assessment of candidates:

  • A master’s degree equivalent to a Danish 5-year MSc degree
  • The grade point average achieve
  • Professional qualifications relevant to the PhD programme
  • Previous research publications desirable
  • Relevant research experience related to the subject area of the project, such as:
    • Experience with Matlab, R or equivalent computational tools to handle large datasets
    • State-of-the art budding yeast and Arabidopsis Molecular Genetics approaches, such as Chromatin Immuno Precipitation (ChIP) and RNA analysis techniques
    • Experience in the areas of Chromatin, Non-coding RNA, Pol II Transcription
    • Experience with high-throughput approaches, e.g. Next Generation Sequencing
    • Other professional activities
    • Language skills, fluency in English
    • Marks obtained during the first year of study on the master programme (only relevant for applicants applying for a 4-year scholarship)
    • Dedication, hard work and the ability to collaborate and profit from interactions with other members of the research group are additional success criteria
Formal requirements
Applicants should hold an MSc degree in biochemistry, molecular biology, microbiology or plant biology, and should be fluent in both spoken and written English.

Terms of employment
The position is covered by the Memorandum on Job Structure for Academic Staff.

Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.

The starting salary is currently at a minimum DKK 309,109 including annual supplement (+ pension up to DKK 42,699). Negotiation for salary supplement is possible.

Application Procedure
The application, in English, must be submitted electronically by clicking APPLY NOW below.

 Applications must include:
  • Cover Letter, detailing your motivation and background for applying for the specific PhD project
  • CV
  • Diploma and transcripts of records (BSc and MSc)
  • Other information for consideration, e.g. list of publications (if any)
  • Personal Recommendations
  • Documentation of English language qualifications, (general rules and guidelines, p. 5.).
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

The deadline for applications is 15 June 2017. Applications received after the deadline for applications will not be considered.

 After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee. Afterwards an assessment committee will be appointed to evaluate the selected applications. The applicants will be notified of the composition of the committee and the final selection of a successful candidate will be made by the Head of Department, based on the recommendations of the assessment committee and the interview committee.

The main criterion for selection will be the research potential of the applicant and the above mentioned skills. The successful candidate will then be requested to formally apply for enrolment as a PhD student at the PhD school of Science. You can read more about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

Questions
For specific information about the PhD scholarship, please contact the principal supervisor: Sebastian Marquardt, sebastian.marquardt@plen.ku.dk , +4535331305

 

General information about PhD programmes at SCIENCE is available at http://www.science.ku.dk/phd.
APPLY NOW

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Contact

Sebastian Marquardt

Info

Application deadline: 15-06-2017
Employment type: Limited period
Employment start: 01-09-2017
Department/Location: Department of Plant and Environmental Sciences

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