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PhD fellowship in Advanced Drug Delivery Systems for Brain Cancer Treatment

Department of Pharmacy is offering a three-year PhD fellowship in Advanced Drug Delivery Systems for Brain Cancer Treatment. The PhD fellowship is financed by the Danish Council for Independent Research | Technology and Production Sciences (Det Frie Forskningsråd for Teknologi og Produktion (FTP)), reference DFF - 7017-00065, and involves collaboration with Prof. Seyed Moein Moghimi (School of Medicine, Pharmacy and Health, University of Durham, UK) and different international collaborators. The fellowship is available from 01.09.2017 or as soon as possible thereafter. 
 
Project description 
The main problems in treating brain tumors are the limited permeability of the blood brain barrier (BBB) to anti-cancer therapeutics and the high sensitivity of healthy surrounding tissues. Recent studies showed that nanoparticlulate formulations are attractive candidates for glioblastoma therapy as they can migrate the compromised regions of the BBB (tumor enhanced permeability retention effect) and release their drug cargo at the vicinity of the brain tumors. Through precision nano-engineering and an interdisciplinary integrated approach, this project focuses on the formulation of immune-safe non-lamellar liquid crystalline nanocarriers for bioimaging of - and concomitant drug delivery to - cancerous brain tumors, by dual encapsulation of an imaging probe and an anticancer drug in the internal nanostructures of cubosomes and hexosomes. Cubosomes and hexosomes are intriguing nanoparticles with unique self assemblies providing reservoirs for accommodating imaging probes as well as poorly water-soluble anticancer drugs. 
 
Principal supervisor  
Associate Professor Anan Yaghmur, Department of Pharmacy,  
E-mail:  anan.yaghmur@sund.ku.dk, direct phone: +45 35336541
 
Required qualifications  
As an applicant you must have: 
  • Obtained a Master´s degree in nanomedicine, or a closely related subject prior to the starting date.  
  • Fluency in English and excellent communication skills  
  • The ability to work in an interdisciplinary environment. 
  • The ability to travel for performing experiments abroad. 
Preferred qualifications 
  • We are looking for a highly motivated individual with a strong background in connection with cancer research, and previous experience in tissue culture, cell biology, in vivo testing. and molecular imaging are advantageous.  
Job description 
Your key tasks as a PhD fellow at the Faculty are to: 
  • Carry through an independent research project under supervision 
  • Write scientific articles and the PhD thesis on the grounds of your research project 
  • Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points 
  • Obtain experience with teaching or other types of dissemination related to your PhD project 
  • Participate in the undergraduate teaching of students in pharmaceutical sciences 
  • Participate in national and international congresses and scientific meetings  
  • Stay at an external research institution, preferably abroad  
Key criteria for the assessment of applicants 
  • Professional qualifications relevant to the PhD programme  
  • Relevant work experience  
  • Previous publications  
  • The grade point average achieved  
  • Other professional activities  
  • Language skills  
  • The successful applicant is also required to be enterprising and to possess good interpersonal skills 
Formal requirements 
The successful applicant will be requested to formally apply for enrolment as a PhD student at the Faculty of Health and Medical Sciences according to the rules stipulated in the Ministerial order on the PhD programme at the universities (PhD order) from the Ministry of Science, Innovation, and Higher Education and the guidelines for the PhD programme at the Faculty of Health and Medical Sciences.  
 
The PhD student is expected to be affiliated to the graduate programme in pharmaceutical sciences, Drug Research Academy.  
 
Terms of employment 
The position as a PhD fellow is available for a 3-year period. 
 
Salary and other terms and conditions of appointment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant professional organizations. The position is covered by the Protocol on Job Structure.  
Minimum monthly salary is DKK 26,073 (taxable) + pension contribution. 
 
Application procedure 
The application, in English, must be submitted electronically by clicking APPLY NOW below. 
Your application must include:  
  • Cover letter: Letter stating the interest in and qualifications for the project (max. one page)  
  • Full CV  
  • Diploma and transcripts of records: Master´s degree diploma (including grade transcripts for bachelor´s and master´s degrees). Applicants with a Master´s degree from abroad should also enclose a short description of the grading scale used 
  • Possible publication list  
  • Other information to consider: Possible references and recommendations  
The University of Copenhagen wishes to encourage everyone interested in this post to apply, regardless of personal background. 
 
Deadline for applications 
06.08.2017. Please note that only online applications will be accepted. 
Applications received later than this date will not be considered.  
 
Post application procedure 
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee.  
All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee.  
Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk 
 
The Appointments Committee consists of the supervision group and the Head of Department who is the authorized recruitment manager. The Expert Assessment Committee consists of the principal supervisor. 
An answer as to the granting of the fellowship can be expected approx. 4 weeks after application deadline. 
 
Questions 
For further information, applicants may contact the supervisor or Administrator Marianne W. Jørgensen, e-mail: marianne.joergensen@sund.ku.dk, direct phone: +45 3533 6449.  
For more information on working and living in Denmark visit http://ism.ku.dk (International staff mobility) and https://www.workindenmark.dk 
 
APPLY NOW

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Contact

Anan Yaghmur

Info

Application deadline: 06-08-2017
Employment start: 01-10-2017
Working hours: Full time
Department/Location: Institut for Farmaci

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